Cytogenetics Mock Test 4

10%

Question 1 of 10

1. Which of the following is not true about type II restriction endonuclease?

In this case the recognition sequence is asymmetric

Here Clevage and Methylation are by different enzymes

It can’t cleave at methylated sequences

It cleaves within the recognition sequence

Question 1 of 10

Question 2 of 10

2. It is good that Guanine methyl transferase is absent in human beings.

True

False

Question 2 of 10

Question 3 of 10

3. Which of the following can act as an intragenic suppressor mutation to a Frame shift mutation?

Another frame shift mutation

Missense mutation

Non sense mutation

Transition

Question 3 of 10

Question 4 of 10

4. Which of the following factors in MMR can recognize the mismatch?

Mut H

Mut S

Mut L

XRCC1

Question 4 of 10

Question 5 of 10

5. 6, 4 PP are brought about by which type of mutagen?

Methylase

Phosphatase

Radiation

Base Analogue

Question 5 of 10

Question 6 of 10

6. If the nick is at 5’ end of the mismatch which of the following will be recruited?

Exonuclease I

Ruv D

Exonuclease X

Rec J

Question 6 of 10

Question 7 of 10

7. All mutations result in the production of a mutant.

False

True

Question 7 of 10

Question 8 of 10

8. In an experiment to check mutagenicity of a substance, we feed the mutagen to a rat and then use the rat _______ extract within the media. This ensures_____________

Kidney; the mutagen is broken down

Liver; the media has adequate iron from rat RBC

Liver; the mutagen is processed

Kidney; the mutagen can be at a higher concentration

Question 8 of 10

Question 9 of 10

9. In which of the following will you expect plasmids to be absent?

Streptococcus sp

Panthera sp

Schizosaccharomyces pombe

Haemophilis sp