Drug and Pharmaceutical Biotechnology Mock Test 3

10%

Question 1 of 10

1. Bioavailability of glutathione in the body doesn’t determine the threshold of a toxic response.

True

False

Question 1 of 10

Question 2 of 10

2. The principle of prodrug design is known as chemical formulation.

False

True

Question 2 of 10

Question 3 of 10

3. Which enzyme’s presence is of utmost importance for the 2nd step of sulphation?

Transferase

UDP-glucuronyl transferase

Sulfotransferase

Amidases

Question 3 of 10

Question 4 of 10

4. Microsome are selective to ____________

Basic drugs

Lipid soluble drugs

Water-soluble drugs

Acidic drugs

Question 4 of 10

Question 5 of 10

5. Where are non-microsomal enzymes present?

Inside lysosomes

In oxysomes

In the Golgi apparatus

In the cytoplasm in soluble form

Question 5 of 10

Question 6 of 10

6. Fat-free diet depresses cytochrome P-450 level.

True

False

Question 6 of 10

Question 7 of 10

7. Which enzymes catalyses the hydrolysis of amides?

Esterase

Amidases

Aminodases

Amydases

Question 7 of 10

Question 8 of 10

8. Alcohol is the inducer for which drug?

Pentobarbital

Cortisol

Oral contraceptives

Meprobamate

Question 8 of 10

Question 9 of 10

9. Which of the following is not a characteristic of the moieties that are transferred to the substrate in phase II reactions?

Strong polar groups are attached

Simple endogenous molecules are transferred

Strong nonpolar groups are attached

Large molecular sized groups are attached

Question 9 of 10

Question 10 of 10

10. Which xenobiotics yield free radicles on metabolic activation?

Quinones

Aflatoxin

Thalidomide

Benzopyrene

Question 10 of 10