Drug and Pharmaceutical Biotechnology Mock Test 4

10%

Question 1 of 10

1. Which of the following will be a disadvantage for the physiologic model?

Correlation of data in several animal species

The model gives an exact description of the drug concentration-time profile for any organ

Prediction of drug concentration in various body regions

Obtaining experimental data for each of the organs

Question 1 of 10

Question 2 of 10

2. Which of the following is not a disadvantage of site-specific drug delivery?

Less distribution time

No penetrable to the target tissue

May lead to toxic effects on other non-target tissues

May get diluted

Question 2 of 10

Question 3 of 10

3. What will be the fraction of unbound drug if the unbound drug concentration is 0.99 g/ml and total plasma concentration is 160 g/ml?

0.618

0.010

1.61

0.006

Question 3 of 10

Question 4 of 10

4. In plasma drug concentration versus time graph as shown in the picture, what should be the correct option for the marked place?

Minimum effective concentration

Maximum safe concentration

Onset of action

Therapeutic range

Question 4 of 10

Question 5 of 10

5. What will be the renal clearance if the rate of urinary excretion is 625 ml/min and plasma drug concentration is 4.2 ng/ml?

140ml²/ng min

148.80ml²/ng min

152ml²/ng min

150ml²/ng min

Question 5 of 10

Question 6 of 10

6. Which of the following compounds are used as agents to determine Glomerular Filtration Rate?

Calcium ion

Creatinine

Calcium carbonate

Albumin

Question 6 of 10

Question 7 of 10

7. How to prevent hepatic first-pass metabolism for corticosteroids?

Form esters and ether products

Providing intravenously

Providing orally

By enhancing lipophilicity

Question 7 of 10

Question 8 of 10

8. What will be the elimination rate if the clearance is 130ml/min and drug concentration is 0.8 g/ml?

104g/min

140g/min

100g/min

130g/min

Question 8 of 10

Question 9 of 10

9. In the following diagram which organ name should be in the place of ‘?’?

Small intestine

Liver

Large intestine

Kidney

Question 9 of 10

Question 10 of 10

10. Which organ comprises the peripheral compartment in a two compartment model?

Liver

Lungs

Kidneys

Muscles

Question 10 of 10