Genetic Engineering Mock Test 10

10%

Question 1 of 10

1. Cells deficient in thymidine kinase (TK) are also killed in HAT medium.

False

True

Question 1 of 10

Question 2 of 10

2. The amount of expression of DNA inserted into a vector _______ on promoter and ______ on chromosomal location.

depends, depends also

doesn’t depends, but depends

neither depends, nor depends

depends only on, not depends

Question 2 of 10

Question 3 of 10

3. Hygromycin is used as a selectable marker in mammalian cultured cells. It is used for ____________

inhibiting DNA binding process

initiating protein synthesis

inhibiting protein synthesis

initiating DNA binding process

Question 3 of 10

Question 4 of 10

4. If controlled inactivation of a gene is carried out and some of the consequences when inactivation of a target gene is deleterious are avoided. It is referred as ____________

specialized gene targeting

specific gene targeting

controlled gene targeting

conditional gene targeting

Question 4 of 10

Question 5 of 10

5. Transient gene silencing can be carried out by microinjecting ______

double stranded DNA

single stranded RNA

double stranded RNA

either double stranded DNA or RNA

Question 5 of 10

Question 6 of 10

6. Cells whose contents have been removed and replaced, by swelling and shrinking in solutions of suitable osmotic strength are called as ____________

protoplast

vacuole

ghosts

shrunken cells

Question 6 of 10

Question 7 of 10

7. Puromycin is a protein synthesis inhibitor. It is conferred by _______ gene.

streptococcal

streptomyces

bacilovirus

both streptococcal and streptomyces

Question 7 of 10

Question 8 of 10

8. The size of the viral genome is large and thus poses a problem. This problem can be resolved by using ____________

transfer vector

fusion vector

co-integration plasmid

hybrid vector

Question 8 of 10

Question 9 of 10

9. If a mutation perturbs the structure, then stability and folding are not affected.

False

True

Question 9 of 10

Question 10 of 10

10. If the DNA is linearized, what is the effect on the recombination frequency?

The recombination may increase or decrease depending on the amount of DNA

The recombination frequency decreases

There is no effect on the recombination frequency

The recombination frequency increases

Question 10 of 10